HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 3-[2-(2,5-Dimethyl-phenyl)-2H-pyrazol-3-yl]-1-phenyl-1H-pyridazin-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | (2,5-Dimethylphenyl)hydrazine | HCID 853149 | — |
| Reactant | (E)-3-(3-(Dimethylamino)acryloyl)-1-phenylpyridazin-4(1H)-one | HCID 12742246 | — |
| Product | 3-[2-(2,5-Dimethyl-phenyl)-2H-pyrazol-3-yl]-1-phenyl-1H-pyridazin-4-one | HCID 46219450 | 74% |
Reaction Steps
The product was obtained starting from 3-((E)-3-Dimethylamino-acryloyl)-1-phenyl-1H-pyridazin-4-one (A-1) and 2,5-dimethyl-phenylhydrazine×HCl according to the method described for Example 1 in 74% yield. MS: M=343.2 (M+H)+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08178538B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-6b15fd9d320d422ab975493b743f5307 |
| Source note | uspto-grants-2012_05 |