HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Hydrazinobenzoic acid → 4-{5-[4-Oxo-1-(3-trifluoromethoxy-phenyl)-1,4-dihydro-pyridazin-3-yl]-pyrazol-1-yl}-benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Hydrazinobenzoic acid | HCID 12089 | — |
| Reactant | 3-((E)-3-Dimethylamino-acryloyl)-1-(3-trifluoromethoxy-phenyl)-1H-pyridazin-4-one | HCID 59370123 | — |
| Product | 4-{5-[4-Oxo-1-(3-trifluoromethoxy-phenyl)-1,4-dihydro-pyridazin-3-yl]-pyrazol-1-yl}-benzoic acid | HCID 46219934 | — |
Reaction Steps
Reaction of 3-((E)-3-Dimethylamino-acryloyl)-1-(3-trifluoromethoxy-phenyl)-1H-pyridazin-4-one (A-6) and 4-hydrazino-benzoic acid according to example 43 gave the desired product. MS: M=442.9 (M)+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08178538B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-87e5cc3f2bc443eab551539708255a19 |
| Source note | uspto-grants-2012_05 |