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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1924595Generated: October 31, 2026

[3-(Trifluoromethoxy)phenyl]hydrazine → 1-(3-Methanesulfonyl-phenyl)-3-[2-(3-trifluoromethoxy-phenyl)-2H-pyrazol-3-yl]-1H-pyridazin-4-one

https://huagongshe.com/reaction/1924595

Reaction equation

Participants

RoleNameHCIDCharge
Reactant[3-(Trifluoromethoxy)phenyl]hydrazineHCID 5194226—
Reactant3-((E)-3-Dimethylamino-acryloyl)-1-(3-methansulfonyl-phenyl)-1H-pyridazin-4-oneHCID 59370171—
Product1-(3-Methanesulfonyl-phenyl)-3-[2-(3-trifluoromethoxy-phenyl)-2H-pyrazol-3-yl]-1H-pyridazin-4-oneHCID 59370093—

Reaction Steps

The product was obtained starting from 3-((E)-3-Dimethylamino-acryloyl)-1-(3-methansulfonyl-phenyl)-1H-pyridazin-4-one (A-7) and 3-trifluoromethoxy-phenylhydrazine according to the method described for example 43. MS: M=477.2 (M+H)+

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08178538B2
Source datasetuspto-grants-2012_05
ORD IDord-8a361635692b4d119990571711bec583
Source noteuspto-grants-2012_05