HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Hydrazinylbenzonitrile → 3-{5-[1-(2,2-Difluoro-benzo[1,3]dioxol-4-yl)-4-oxo-1,4-dihydro-pyridazin-3-yl]-pyrazol-1-yl}-benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Hydrazinylbenzonitrile | HCID 1488145 | — |
| Reactant | 1-(2,2-Difluoro-benzo[1,3]dioxol-4-yl)-3-((E)-3-dimethylamino-acryloyl)-1H-pyridazin-4-one | HCID 59370134 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 3-{5-[1-(2,2-Difluoro-benzo[1,3]dioxol-4-yl)-4-oxo-1,4-dihydro-pyridazin-3-yl]-pyrazol-1-yl}-benzonitrile | HCID 59370047 | — |
Reaction Steps
The product was obtained starting from 1-(2,2-Difluoro-benzo[1,3]dioxol-4-yl)-3-((E)-3-dimethylamino-acryloyl)-1H-pyridazin-4-one (A-15) and 3-hydrazino-benzonitrile in ethanol as solvent according to the method described for example 91. MS: M=420.2 (M+H)+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08178538B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-1f75eacfa4a04802b7ed182bd757d3da |
| Source note | uspto-grants-2012_05 |