HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Fluorophenylhydrazine hydrochloride → 1-(4-Difluoromethoxy-phenyl)-3-[2-(2-fluoro-phenyl)-2H-pyrazol-3-yl]-1H-pyridazin-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Fluorophenylhydrazine hydrochloride | HCID 423844 | — |
| Reactant | 1-(4-Difluoromethoxy-phenyl)-3-((E)-3-dimethylamino-acryloyl)-1H-pyridazin-4-one | HCID 59369978 | — |
| Product | 1-(4-Difluoromethoxy-phenyl)-3-[2-(2-fluoro-phenyl)-2H-pyrazol-3-yl]-1H-pyridazin-4-one | HCID 59370090 | — |
Reaction Steps
The product was obtained starting from 1-(4-Difluoromethoxy-phenyl)-3-((E)-3-dimethylamino-acryloyl)-1H-pyridazin-4-one (A-9) and 2-fluoro-phenylhydrazine according to the method described for example 91. MS: M=399.1 (M+H)+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08178538B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-cbfb077a4160418f8aa600cdc20d1616 |
| Source note | uspto-grants-2012_05 |