HuagongsheHuagongshe Chemistry Print Report · For research reference only
(E)-3-(3-(Dimethylamino)acryloyl)-1-phenylpyridazin-4(1H)-one → 3-[2-(6-Fluoro-quinolin-4-yl)-2H-pyrazol-3-yl]-1-phenyl-1H-pyridazin-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (E)-3-(3-(Dimethylamino)acryloyl)-1-phenylpyridazin-4(1H)-one | HCID 12742246 | — |
| Reactant | 6-Fluoro-4-hydrazinoquinoline | HCID 17039615 | — |
| Product | 3-[2-(6-Fluoro-quinolin-4-yl)-2H-pyrazol-3-yl]-1-phenyl-1H-pyridazin-4-one | HCID 59369979 | — |
Reaction Steps
The product was obtained starting from 3-((E)-3-Dimethylamino-acryloyl)-1-phenyl-1H-pyridazin-4-one (A-1) and (6-fluoro-quinolin-4-yl)-hydrazine according to the method described for example 1. MS: M=384.1 (M+H)+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08178538B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-f7e5d2c8104347d091d2786181ab8cfb |
| Source note | uspto-grants-2012_05 |