HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Fluoro-4-hydrazinyl-2-methyl-quinoline → 3-[2-(6-Fluoro-2-methyl-quinolin-4-yl)-2H-pyrazol-3-yl]-1-(3-methoxy-phenyl)-1H-pyridazin-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Fluoro-4-hydrazinyl-2-methyl-quinoline | HCID 493235 | — |
| Reactant | 3-((E)-3-Dimethylamino-acryloyl)-1-(3-methoxy-phenyl)-1H-pyridazin-4-one | HCID 59369989 | — |
| Product | 3-[2-(6-Fluoro-2-methyl-quinolin-4-yl)-2H-pyrazol-3-yl]-1-(3-methoxy-phenyl)-1H-pyridazin-4-one | HCID 59370151 | — |
Reaction Steps
The product was obtained starting from 3-((E)-3-Dimethylamino-acryloyl)-1-(3-methoxy-phenyl)-1H-pyridazin-4-one (A-5) and (6-fluoro-2-methyl-quinolin-4-yl)-hydrazine according to the method described for example 91. MS: M=428.2 (M+H)+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08178538B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-c2c1310714e249a08335058cd44e0a02 |
| Source note | uspto-grants-2012_05 |