HuagongsheHuagongshe Chemistry Print Report · For research reference only
(3-Methyl-isothiazol-5-yl)-hydrazine → 3-[2-(3-Methyl-isothiazol-5-yl)-2H-pyrazol-3-yl]-1-(4-trifluoromethoxy-phenyl)-1H-pyridazin-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (3-Methyl-isothiazol-5-yl)-hydrazine | HCID 55282001 | — |
| Reactant | 3-((E)-3-Dimethylamino-acryloyl)-1-(4-trifluoromethoxy-phenyl)-1H-pyridazin-4-one | HCID 59370034 | — |
| Product | 3-[2-(3-Methyl-isothiazol-5-yl)-2H-pyrazol-3-yl]-1-(4-trifluoromethoxy-phenyl)-1H-pyridazin-4-one | HCID 59370066 | — |
Reaction Steps
The product was obtained starting from 3-((E)-3-Dimethylamino-acryloyl)-1-(4-trifluoromethoxy-phenyl)-1H-pyridazin-4-one (A-8) and (3-methyl-isothiazol-5-yl)-hydrazine according to the method described for example 43. MS: M=420.0 (M+H)+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08178538B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-00c0357d2d1e436dbb5466a5ac4a771c |
| Source note | uspto-grants-2012_05 |