HuagongsheHuagongshe Chemistry Print Report · For research reference only
8-Hydrazinylisoquinoline → 3-[3-(2-Isoquinolin-8-yl-2H-pyrazol-3-yl)-4-oxo-4H-pyridazin-1-yl]-N,N-dimethyl-benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 8-Hydrazinylisoquinoline | HCID 12412857 | — |
| Reactant | 3-[3-((E)-3-Dimethylamino-acryloyl)-4-oxo-4H-pyridazin-1-yl]-N,N-dimethyl-benzenesulfonamide | HCID 59370163 | — |
| Product | 3-[3-(2-Isoquinolin-8-yl-2H-pyrazol-3-yl)-4-oxo-4H-pyridazin-1-yl]-N,N-dimethyl-benzenesulfonamide | HCID 59370081 | — |
Reaction Steps
The product was obtained starting from 3-[3-((E)-3-Dimethylamino-acryloyl)-4-oxo-4H-pyridazin-1-yl]-N,N-dimethyl-benzenesulfonamide (A-12) and isoquinolin-8-yl-hydrazine according to the method described for example 91. MS: M=473.3 (M+H)+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08178538B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-2b411900d4654ee784c43243d4ddc1ca |
| Source note | uspto-grants-2012_05 |