HuagongsheHuagongshe Chemistry Print Report · For research reference only
7-Chloro-4-hydrazinylquinoline → 3-[2-(7-Chloro-quinolin-4-yl)-2H-pyrazol-3-yl]-1-[3-(piperidine-1-sulfonyl)-phenyl]-1H-pyridazin-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 7-Chloro-4-hydrazinylquinoline | HCID 32109 | — |
| Reactant | 3-((E)-3-Dimethylamino-acryloyl)-1-[3-(piperidine-1-sulfonyl)-phenyl]-1H-pyridazin-4-one | HCID 59370113 | — |
| Product | 3-[2-(7-Chloro-quinolin-4-yl)-2H-pyrazol-3-yl]-1-[3-(piperidine-1-sulfonyl)-phenyl]-1H-pyridazin-4-one | HCID 59370106 | — |
Reaction Steps
The product was obtained starting from 3-((E)-3-Dimethylamino-acryloyl)-1-[3-(piperidine-1-sulfonyl)-phenyl]-1H-pyridazin-4-one (A-26) and (7-chloro-quinolin-4-yl)-hydrazine according to the method described for example 91. MS: M=547.2 (M+H)+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08178538B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-d759b30d1e6e4b21a74135fd33ab01ad |
| Source note | uspto-grants-2012_05 |