Phenylhydrazine → 3-(2-Phenyl-2H-pyrazol-3-yl)-1-(3-trifluoromethanesulfonyl-phenyl)-1H-pyridazin-4-one

HRID 1924749Notes

Reaction equation

HRID 1924749 reaction equation
C[N:2](C)/[CH:3]=[CH:4]/[C:5]([C:7]1[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]2[CH:19]=[CH:18][CH:17]=[C:16]([S:20]([C:23]([F:26])([F:25])[F:24])(=[O:22])=[O:21])[CH:15]=2)[N:8]=1)=O.[C:28]1([NH:34]N)[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1>>[C:28]1([N:34]2[C:5]([C:7]3[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]4[CH:19]=[CH:18][CH:17]=[C:16]([S:20]([C:23]([F:24])([F:25])[F:26])(=[O:22])=[O:21])[CH:15]=4)[N:8]=3)=[CH:4][CH:3]=[N:2]2)[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1

Participants

3

Reactant 2

HCID 7516PhenylhydrazineHCID 593701323-((E)-3-Dimethylamino-acryloyl)-1-(3-trifluoromethansulfonyl-phenyl)-1H-pyridazin-4-one

Product 1

HCID 462204693-(2-Phenyl-2H-pyrazol-3-yl)-1-(3-trifluoromethanesulfonyl-phenyl)-1H-pyridazin-4-one

Procedure

The product was obtained starting from 3-((E)-3-Dimethylamino-acryloyl)-1-(3-trifluoromethansulfonyl-phenyl)-1H-pyridazin-4-one (A-33) and phenylhydrazine according to the method described for example 1. MS: M=447.1 (M+H)+

Workup

  1. customThe product was obtained

Sources & evidence

ORD record
ord-e7e95791e05642c882e9ef0a8e545c39
Source dataset
uspto-grants-2012_05
Patent number
US08178538B2

Reaction notes

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