HRID1924781

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID2783396

2-Fluoropyridine-4-boronic acid

C5H5BFNO2

结构：CC(C)(CO)c1ccc(C(=O)Nc2nc3ccc(Br)nc3s2)cc1

HCID58015383

未命名化合物

PRODUCTS

生成物

结构：CC(C)(CO)c1ccc(C(=O)Nc2nc3ccc(-c4ccnc(F)c4)nc3s2)cc1

HCID44548622

N-(5-(2-fluoropyridin-4-yl)thiazolo[5,4-b]pyridin-2-yl)-4-(1-hydroxy-2-methylpropan-2-yl)benzamide

C22H19FN4O2S

收率 38%

PROCEDURE

实验过程

The titled compound (yield=38%, light yellow solid) was prepared using a procedure analogous to that described in connection with 10 (Example 10) except that 2F (Example 2) and 2-fluoropyridin-4-ylboronic acid were used as starting materials. 1H NMR (400 MHz, DMSO-d6) δ ppm 1.27 (s, 6H) 3.49 (d, J=3.03 Hz, 2H) 4.78 (br. s., 1H) 7.59 (d, J=8.59 Hz, 2H) 7.91 (s, 1H) 8.06-8.16 (m, 3H) 8.27-8.36 (m, 2H) 8.38 (d, J=5.31 Hz, 1H) 13.11 (s, 1H); ESI-MS: m/z 423.0 (M+H)+.