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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1925019Generated: October 28, 2026

Hydrochloric Acid → HCID 135995200, compound

https://huagongshe.com/reaction/1925019

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 59448347HCID 59448347—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 135995200HCID 135995200—

Reaction Steps

(5-(4,5-dimethyl-1,3-thiazol-2-yl)-2,4-bis(methyloxy)pyrimidine) (Prep14, 118 mg, 0.470 mmol) in HCl (5.87 ml, 23.48 mmol) 4M in dioxane was stirred in a closed tube at 90° C. for 1.5 hour. Then the mixture was cooled to rt and the solvent evaporated under vacuum to afford the title compound as a pale grey solid (153 mg)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08178549B2
Source datasetuspto-grants-2012_05
ORD IDord-5d8f4f088ea94406982bd822478c6c80
Source noteuspto-grants-2012_05