Hydrochloric Acid → HCID 67519670, compound

HRID 1925026Notes

Reaction equation

HRID 1925026 reaction equation
[S:1]1[CH:5]=[C:4]([C:6]2[C:7]([O:14]C)=[N:8][C:9]([O:12]C)=[N:10][CH:11]=2)[CH:3]=[N:2]1.[ClH:16]>O1CCOCC1>[ClH:16].[S:1]1[CH:5]=[C:4]([C:6]2[C:7](=[O:14])[NH:8][C:9](=[O:12])[NH:10][CH:11]=2)[CH:3]=[N:2]1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 59448381HCID 59448381, compound

Product 1

HCID 67519670HCID 67519670, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

5-(4-isothiazolyl)-2,4-bis(methyloxy)pyrimidine (Prep22, 686 mg, 2.427 mmol) was suspended in 4M HCl solution in 1,4-dioxane (25 ml). After 1 h at 90° C., the solvent was evaporated. 696.8 mg of the title compound were isolated as a yellow solid.

Workup

  1. customthe solvent was evaporated

Sources & evidence

ORD record
ord-6334a3e32af84d6f9589fda9500daf64
Source dataset
uspto-grants-2012_05
Patent number
US08178549B2

Reaction notes

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