Hydrochloric Acid → HCID 67519603, compound

Participants

Reaction Steps

5-(1,3-dimethyl-1H-pyrazol-5-yl)-1-(3-{(1S,5R)-1-[4-(trifluoromethyl)phenyl]-3-azabicyclo[3.1.0]hex-3-yl}propyl)-2,4(1H,3H)-pyrimidinedione (E3, 90 mg, 0.177 mmol) was dissolved in diethyl ether (2 ml) and HCl 1M in diethylether (0.177 mmol, 0.177 ml) was added dropwise. The white solid obtained was triturated in Et2O (2×4 ml) to give, after filtration, the title compound (50 mg, 0.078 mmol).

Provenance & Evidence