Hydrochloric Acid → HCID 67519639, compound

Participants

Reaction Steps

5-(5-methyl-1,3,4-thiadiazol-2-yl)-1-(3-{(1S,5R)-1-[4-(trifluoromethyl)phenyl]-3-azabicyclo[3.1.0]hex-3-yl}propyl)-2,4(1H,3H)-pyrimidinedione (E5, 7 mg, 0.015 mmol) was dissolved in diethyl ether (1 ml) and hydrochloric acid 1M in diethylether (0.030 ml, 0.030 mmol) was added. The solid obtained was triturated in diethylether (2×1 mL) giving the title compound as a white solid (8.8 mg, 0.014 mmol).

Provenance & Evidence