Hydrochloric Acid → HCID 67519722, compound

Participants

Reaction Steps

5-(4,5-dimethyl-1,3-thiazol-2-yl)-1-(3-{(1S,5R)-1-[4-(trifluoromethyl)phenyl]-3-azabicyclo[3.1.0]hex-3-yl}propyl)-2,4(1H,3H)-pyrimidinedione (E 7, 3 mg, 6.12 μmol) was suspended in Diethyl ether (0.5 ml). 1M Hydrochloric acid (7.34 μl, 7.34 μmol) in Et2O was added and the resulting solid was triturated with Et2O (3×0.3 mL) to afford the title compound as a yellowish solid (2.9, mg, 77% yield)

Provenance & Evidence