Hydrochloric Acid → 1-(3-{(1S,5R)-1-[4-(trifluoromethyl)phenyl]-3-azabicyclo[3.1.0]hex-3-yl}propyl)-5-[3-(trifluoromethyl)-1H-pyrazol-1-yl]-2,4(1H,3H)-pyrimidinedione dihydrochloride

Participants

Reaction Steps

1-(3-{(1S,5R)-1-[4-(trifluoromethyl)phenyl]-3-azabicyclo[3.1.0]hex-3-yl}propyl)-5-[3-(trifluoromethyl)-1H-pyrazol-1-yl]-2,4(1H,3H)-pyrimidinedione (E20, 10.3 mg, 0.020 mmol) was dissolved in Diethyl ether (2 ml). 1M solution of HCl in Diethyl ether (0.044 ml, 0.044 mmol) was added. The solvent was evaporated to obtain 11.6 mg of the title compound as a yellow powder.

Provenance & Evidence