HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 86644397, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 25253141 | HCID 25253141 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 86644397 | HCID 86644397 | — |
Reaction Steps
1-(3-{(1S,5R)-1-[4-(trifluoromethyl)phenyl]-3-azabicyclo[3.1.0]hex-3-yl}propyl)-5-[3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl]-2,4(1H,3H)-pyrimidinedione (E26, 9.4 mg, 0.014 mmol) was dissolved and sonicated in Diethyl ether (1 ml) to give a colorless solution. 1.0 M solution of HCl in Diethyl ether (0.035 ml, 0.035 mmol) was added at room temperature. After 3 min and the solvent evaporated in vacuo. Obtained 9.7 mg of the title compound as a white powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08178549B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-47942eb9385f43dea97f68d0c548d665 |
| Source note | uspto-grants-2012_05 |