HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 67519686, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | HCID 25253295 | HCID 25253295 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 67519686 | HCID 67519686 | — |
Reaction Steps
5-(2,4-dimethyl-1,3-thiazol-5-yl)-1-(4-{(1S,5R)-1-[4-(trifluoromethyl)phenyl]-3-azabicyclo[3.1.0]hex-3-yl}butyl)-2,4(1H,3H)-pyrimidinedione (E35) was dissolved in DCM and treated with HCl 1N solution in Et2O (2.2 eq) to form the title compound (31 mg, 0.054 mmol) as a white powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08178549B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-261e3fea551c47618702cabde6b405e2 |
| Source note | uspto-grants-2012_05 |