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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1925179Generated: October 29, 2026

Phenyl Isothiocyanate → 6-Fluoro-5-methyl-[1,2,4]triazolo[4,3-a]pyridine-3-thiol

https://huagongshe.com/reaction/1925179

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenyl IsothiocyanateHCID 7673—
Reactant3-Fluoro-6-hydrazinyl-2-methylpyridineHCID 53403008—
Reactant6-Bromo-[1,2,4]triazolo[4,3-a]pyridine-3-thiolHCID 178527920—
Product6-Fluoro-5-methyl-[1,2,4]triazolo[4,3-a]pyridine-3-thiolHCID 178429743—

Reaction Steps

The title compound was prepared from 3-fluoro-6-hydrazinyl-2-methylpyridine and isothiocyanatobenzene following the procedure described for the synthesis of compound 4A.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08178534B2
Source datasetuspto-grants-2012_05
ORD IDord-eadadd73b20f436a81900f0a32f0615b
Source noteuspto-grants-2012_05