Phenyl Isothiocyanate → 6-Fluoro-5-methyl-[1,2,4]triazolo[4,3-a]pyridine-3-thiol
Reaction equation
[F:1][C:2]1[C:3]([CH3:10])=[N:4][C:5]([NH:8][NH2:9])=[CH:6][CH:7]=1.N(C1C=CC=CC=1)=[C:12]=[S:13].BrC1C=CC2N(C(S)=NN=2)C=1>>[F:1][C:2]1[CH:7]=[CH:6][C:5]2[N:4]([C:12]([SH:13])=[N:9][N:8]=2)[C:3]=1[CH3:10]Participants
4
Procedure
The title compound was prepared from 3-fluoro-6-hydrazinyl-2-methylpyridine and isothiocyanatobenzene following the procedure described for the synthesis of compound 4A.
Sources & evidence
- ORD record
- ord-eadadd73b20f436a81900f0a32f0615b
- Source dataset
- uspto-grants-2012_05
- Patent number
- US08178534B2
Reaction notes
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