4-Chloropyridine-2-carboxamide → HCID 67520303, compound

HRID 1925335Notes

Reaction equation

HRID 1925335 reaction equation
[OH:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[C:8]([C:12]([OH:14])=[O:13])=[CH:7][CH:6]=[CH:5]2.Cl[C:16]1[CH:21]=[CH:20][N:19]=[C:18]([C:22]([NH2:24])=[O:23])[CH:17]=1>>[C:22]([C:18]1[CH:17]=[C:16]([O:1][C:2]2[CH:3]=[C:4]3[C:9](=[CH:10][CH:11]=2)[C:8]([C:12]([OH:14])=[O:13])=[CH:7][CH:6]=[CH:5]3)[CH:21]=[CH:20][N:19]=1)(=[O:23])[NH2:24]

Participants

3

Reactant 2

HCID 3035434-Chloropyridine-2-carboxamideHCID 54638006-Hydroxy-1-naphthoic acid

Product 1

HCID 67520303HCID 67520303, compound

Procedure

6-Hydroxy-1-napthoic acid (2.5 g, 13 mmol) was reacted with 4-chloropicolinamide (WO 02/085857) (2.6 g, 15 mmol) under the conditions of Example 421 Step a to give the title compound as a brown solid. MS (ESI, pos. ion) m/z: 309.2 (M+1). Mass Calc'd for C17H12N2O4: 308.29.

Sources & evidence

ORD record
ord-39463189ba40427e83a7fcbf675a3bf1
Source dataset
uspto-grants-2012_05
Patent number
US08178557B2

Reaction notes

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