HCID 3522175, compound → 2-(4-Aminophenyl)-1-(4-methylpiperazin-1-yl)ethan-1-one

Participants

Reaction Steps

A solution of 1-methyl-4-[(4-nitrophenyl)acetyl]piperazine (1.5 g, 5.70 mmol) in EtOH (30 mL) was reduced over palladium/charcoal (10% wt, 50% wet, 150 mg) with hydrogen under atmospheric pressure and RT for 18 h. The catalyst was separated by filtration through Celite® and the solvent evaporated to the title compound as a brown oil, 1.12 g.

Provenance & Evidence