Hydrochloric Acid → HCID 67521129, compound

HRID 1925522Notes

Reaction equation

HRID 1925522 reaction equation
[CH:1]12[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH:2]1[CH2:11][CH2:12][O:13][C:14]1[CH:19]=[CH:18][C:17]([CH2:20][CH2:21][NH:22]C(=O)OC(C)(C)C)=[CH:16][CH:15]=1)[CH2:8]2.Cl>C(O)C>[CH:3]12[CH2:9][CH:7]3[CH2:6][CH:5]([CH2:10][CH:1]([CH2:8]3)[CH:2]1[CH2:11][CH2:12][O:13][C:14]1[CH:19]=[CH:18][C:17]([CH2:20][CH2:21][NH2:22])=[CH:16][CH:15]=1)[CH2:4]2

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 86649167HCID 86649167, compound

Product 1

HCID 67521129HCID 67521129, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Obtained from Intermediate 75 (0.788 g, 1.97 mmol) and hydrogen chloride 1.25 M in ethanol (26 mL) by the same procedure described in Intermediate 17. The title compound was obtained as a yellow solid (0.5 g, 84%) and used in the next step without further purification. MS (M+): 300.

Sources & evidence

ORD record
ord-1ae92a19045e4072922ba8e1324ea84e
Source dataset
uspto-grants-2012_05
Patent number
US08178679B2

Reaction notes

Loading…