Water → 2-[4-bromo-5-(4-fluorophenyl)-3-(1-methylethyl)-1H-pyrazol-1-yl]pyrimidine
Reaction equation
[Br:1][N:2]1[C:3](=[O:4])[CH2:5][CH2:6][C:7]1=[O:8].[F:9][c:10]1[cH:11][cH:12][c:13](-[c:16]2[cH:17][c:18]([CH:27]([CH3:28])[CH3:29])[n:19][n:20]2-[c:21]2[n:22][cH:23][cH:24][cH:25][n:26]2)[cH:14][cH:15]1.[O:31]=[CH:32][N:33]([CH3:34])[CH3:35].[OH2:30]>>[Br:1][c:17]1[c:16](-[c:13]2[cH:12][cH:11][c:10]([F:9])[cH:15][cH:14]2)[n:20](-[c:21]2[n:22][cH:23][cH:24][cH:25][n:26]2)[n:19][c:18]1[CH:27]([CH3:28])[CH3:29]Participants
5
Sources & evidence
- ORD record
- ord-9d0e4b8f804a4e2396fd43128eed28d1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
Loading…