反应详情

温度

50 °C

Into a sealed tube were added methyl dimethoxyacetate (1.0 g, 7.5 mmol) and 2-bromobenzylamine (1.1 g, 5.8 mmol), this mixture was stirred at 50° C. for 16 h. The completed reaction was transferred to a flask and re-crystallized from heptane yielding the desired product as an off-white solid. MS (ES+): m/z=288.04/289.69 [MH+]. HPLC: tR=2.93 min (ZQ3, polar—5 min).

1. customThe completed reaction
2. customwas transferred to a flask
3. customre-crystallized from heptane yielding the desired product as an off-white solid
4. custom5 min