3-Amino-2-fluorobenzotrifluoride → HCID 67521181, compound

HRID 1926390Notes

Reaction equation

HRID 1926390 reaction equation
F[C:2]1[C:8]([C:9]([F:12])([F:11])[F:10])=[CH:7][CH:6]=[CH:5][C:3]=1[NH2:4].SC1SC2C(C(F)(F)F)=CC=CC=2N=1.[Cl:27][C:28]1[S:29]C2C=CC(Cl)=CC=2N=1>>[Cl:27][C:28]1[S:29][C:2]2[C:8]([C:9]([F:12])([F:11])[F:10])=[CH:7][CH:6]=[CH:5][C:3]=2[N:4]=1

Participants

4

Reactant 3

HCID 1455693-Amino-2-fluorobenzotrifluorideHCID 133148162,5-Dichloro-1,3-benzothiazoleHCID 178506118HCID 178506118, compound

Product 1

HCID 67521181HCID 67521181, compound

Conditions

Temperature
90 °C

Procedure

The title compound was prepared from 2-fluoro-3-trifluoromethylaniline via 2-mercapto-7-trifluoromethyl-1,3-benzothiazole as described for 2,5-dichloro-1,3-benzothiazole except that in the first step the reaction mixture was heated to 90° C. for 4 h.

Sources & evidence

ORD record
ord-20c89ecd561b48d1917be10f90a8064d
Source dataset
uspto-grants-2012_05
Patent number
US08178668B2

Reaction notes

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