HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1926390Generated: November 3, 2026
3-Amino-2-fluorobenzotrifluoride → 2-Chloro-7-(trifluoromethyl)benzo[d]thiazole
https://huagongshe.com/reaction/1926390
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 3-Amino-2-fluorobenzotrifluoride | HCID 145569 | — |
| Reactant | 2,5-Dichloro-1,3-benzothiazole | HCID 13314816 | — |
| Reactant | HCID 178506118 | HCID 178506118 | — |
| Product | 2-Chloro-7-(trifluoromethyl)benzo[d]thiazole | HCID 67521181 | — |
Reaction Steps
The title compound was prepared from 2-fluoro-3-trifluoromethylaniline via 2-mercapto-7-trifluoromethyl-1,3-benzothiazole as described for 2,5-dichloro-1,3-benzothiazole except that in the first step the reaction mixture was heated to 90° C. for 4 h.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08178668B2 |
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| Source dataset | uspto-grants-2012_05 |
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| ORD ID | ord-20c89ecd561b48d1917be10f90a8064d |
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| Source note | uspto-grants-2012_05 |
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