HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1926396Generated: October 26, 2026
2,5-Dichloro-1,3-benzothiazole → 2-Chloro-7-methyl-1,3-benzothiazole
https://huagongshe.com/reaction/1926396
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2,5-Dichloro-1,3-benzothiazole | HCID 13314816 | — |
| Reactant | 2-Fluoro-3-methylaniline | HCID 22734623 | — |
| Reactant | HCID 178424007 | HCID 178424007 | — |
| Product | 2-Chloro-7-methyl-1,3-benzothiazole | HCID 55276485 | — |
Reaction Steps
The title compound was prepared from 2-fluoro-3-methylaniline via 2-mercapto-7-methyl-1,3-benzothiazole as described for 2,5-dichloro-1,3-benzothiazole except that in the first step the reaction mixture was heated to 180° C. for 24 h in a sealed tube.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08178668B2 |
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| Source dataset | uspto-grants-2012_05 |
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| ORD ID | ord-485efb7d20e24fa096649e1404ecc564 |
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| Source note | uspto-grants-2012_05 |
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