HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-6-(trifluoromethoxy)-1,3-benzothiazole → 5-(1-Piperidin-4-yl-1H-pyrazol-4-yl)-3-(6-trifluoromethoxybenzothiazol-2-yl)-pyridin-2-ylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-6-(trifluoromethoxy)-1,3-benzothiazole | HCID 10037924 | — |
| Reactant | 5-(1-Piperidin-4-yl-1H-pyrazol-4-yl)-3-(4-trifluoromethylbenzothiazol-2-yl)-pyridin-2-ylamine | HCID 67520885 | — |
| Product | 5-(1-Piperidin-4-yl-1H-pyrazol-4-yl)-3-(6-trifluoromethoxybenzothiazol-2-yl)-pyridin-2-ylamine | HCID 67521229 | — |
Reaction Steps
Following the procedure for 5-(1-piperidin-4-yl-1H-pyrazol-4-yl)-3-(4-trifluoromethylbenzothiazol-2-yl)-pyridin-2-ylamine, but using 2-chloro-6-trifluoromethoxy-1,3-benzothiazole, the title compound was obtained as yellow solid. MS (ES+): m/z=461.08 [MH+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08178668B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-de623ccfc2f746f9997bbfc49ec74e6f |
| Source note | uspto-grants-2012_05 |