HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1926402Generated: October 30, 2026
2-Bromo-4-(trifluoromethoxy)aniline → 2-Chloro-6-(trifluoromethoxy)-1,3-benzothiazole
https://huagongshe.com/reaction/1926402
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2-Bromo-4-(trifluoromethoxy)aniline | HCID 688296 | — |
| Reactant | 2,5-Dichloro-1,3-benzothiazole | HCID 13314816 | — |
| Reactant | HCID 178506356 | HCID 178506356 | — |
| Product | 2-Chloro-6-(trifluoromethoxy)-1,3-benzothiazole | HCID 10037924 | — |
Reaction Steps
The title compound was prepared from 2-bromo-4-trifluoromethoxyaniline via 2-mercapto-6-trifluoromethoxy-1,3-benzothiazole as described for 2,5-dichloro-1,3-benzothiazole except that in the first step the reaction mixture was heated to 150° C. for 16 h.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08178668B2 |
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| Source dataset | uspto-grants-2012_05 |
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| ORD ID | ord-6f739f5f07154fc5a229c561525adc2c |
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| Source note | uspto-grants-2012_05 |
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