HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chlorobenzo[d]thiazole-5-carbonitrile → 2-[2-Amino-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)-pyridin-3-yl]-benzothiazole-5-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chlorobenzo[d]thiazole-5-carbonitrile | HCID 21985679 | — |
| Reactant | 5-(1-Piperidin-4-yl-1H-pyrazol-4-yl)-3-(4-trifluoromethylbenzothiazol-2-yl)-pyridin-2-ylamine | HCID 67520885 | — |
| Product | 2-[2-Amino-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)-pyridin-3-yl]-benzothiazole-5-carbonitrile | HCID 44158935 | — |
Reaction Steps
Following the procedure for 5-(1-piperidin-4-yl-1H-pyrazol-4-yl)-3-(4-trifluoromethylbenzothiazol-2-yl)-pyridin-2-ylamine, but using 2-chloro-1,3-benzothiazole-5-carbonitrile, the title compound was obtained as yellow solid. MS (ES+): m/z=402.13 [MH+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08178668B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-c0b1e5dd72e547f290c16d3afdeaefc1 |
| Source note | uspto-grants-2012_05 |