HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,3-Difluoroaniline → 7-Bromo-2-iodobenzothiazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,3-Difluoroaniline | HCID 78278 | — |
| Reactant | 2,3-Dibromobenzenamine | HCID 15579998 | — |
| Reactant | 7-Fluoro-2-iodobenzo[d]thiazole | HCID 67521180 | — |
| Product | 7-Bromo-2-iodobenzothiazole | HCID 67521212 | — |
Reaction Steps
The title compound was prepared following the route for 7-fluoro-2-iodo-1,3-benzothiazole from 2,3-difluoroaniline, starting from 2,3-dibromoaniline (prepared according to J. Org. Chem. 1990, 55(9), 2739) and conducting the first step at 95° C. for 4 h.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08178668B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-a30deaeee92c4c7b8ce72a84d935e574 |
| Source note | uspto-grants-2012_05 |