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HRID1926651

反应详情

EQUATION

反应方程式

HRID 1926651 的结构方程式

REACTANTS

反应物

3
结构：Clc1cncc(Cl)n1
HCID78504

2,6-Dichloropyrazine

C4H2Cl2N2

结构：CC(C)(C)OC(=O)N1CCC(Oc2cncc(Cl)n2)CC1
HCID21906088

未命名化合物

2 次

结构：CC(C)(C)OC(=O)N1CC[C@H](O)[C@H](F)C1
HCID40152152

rel-1,1-Dimethylethyl (3R,4S)-3-fluoro-4-hydroxy-1-piperidinecarboxylate

C10H18FNO3

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)N1CC[C@H](Oc2cncc(Cl)n2)[C@H](F)C1
HCID86644306

未命名化合物

PROCEDURE

实验过程

tert-butyl cis-4-[(6-chloropyrazin-2-yl)oxy]-3-fluoropiperidine-1-carboxylate was prepared from 2,6-dichloropyrazine and tert-butyl cis-3-fluoro-4-hydroxypiperidine-1-carboxylate using the conditions described for the preparation of tert-butyl 4-[(6-chloropyrazin-2-yl)oxy]piperidine-1-carboxylate (Compound 1, Step 3). LRMS (ESI) calculated for C14H19ClFN3O3[M+Na]+, 354.1; found 354.1.