Tetrahydrofuran → HCID 69082425, compound

Participants

Reaction Steps

Dissolve 200 mg (0.464 mmol) 6-{[5-(4-methoxyphenyl)-6-phenylfuro[2,3-d]pyrimidin-4-yl]amino}hexanoic acid at RT in 0.75 ml methanol, 0.5 ml THF and a few drops of water, and add 0.464 ml 1 N sodium hydroxide solution. Stir the mixture for 5 min, then concentrate by vacuum evaporation and dry the residue at high vacuum. 221 mg of the target compound is obtained.

Provenance & Evidence