Trifluoroacetic acid → HCID 25096162, compound

Participants

Reaction Steps

Put 280 mg (0.54 mmol) (3-{[5-(4-methoxyphenyl)-6-phenylfuro[2,3-d]pyrimidin-4-yl]oxy}-2,2-dimethylpropoxy)acetic acid tert.-butyl ester in 8 ml dichloromethane. Add 2 ml trifluoroacetic acid and stir for 1 h at RT. Then concentrate by evaporation and mix the residue with petroleum ether. Filter the solid on a frit with suction, and dry at high vacuum. 220 mg (88.1% of theor.) of the target compound is obtained.

Provenance & Evidence