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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1927187Generated: November 2, 2026

Ammonia → Rufinamide

https://huagongshe.com/reaction/1927187

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmoniaHCID 222—
ReactantCGP-47292 methyl esterHCID 22716778—
ProductRufinamideHCID 129228—

Reaction Steps

reacting methyl 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxylate of formula IV with ammonia to obtain rufinamide of formula I.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08183269B2
Source datasetuspto-grants-2012_05
ORD IDord-79c7c4f2988d466e87a620446bf0b5ba
Source noteuspto-grants-2012_05