HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1927394Generated: October 26, 2026
4-tert-Butyltoluene → 4-Tert-butyl-2-chloro-1-methylbenzene
https://huagongshe.com/reaction/1927394
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-tert-Butyltoluene | HCID 7390 | — |
| Reactant | Benyltrimethylammonium tetrachloroiodate | HCID 57347110 | — |
| Product | 4-Tert-butyl-2-chloro-1-methylbenzene | HCID 524337 | 62.3% |
Reaction Steps
A solution of 2 g (13.49 mmol) of 4-tert-butyltoluene is mixed with 5.65 g (13.49 mmol) of benzyltrimethylammonium tetrachloroiodate and stirred at 70° C. for 24 hours. After cooling, the precipitate is filtered off with suction and the filtrate is concentrated. The resulting residue is purified over silica gel (mobile phase: cyclohexane). 1.53 g (8.4 mmol) of the title compound are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08183271B2 |
|---|
| Source dataset | uspto-grants-2012_05 |
|---|
| ORD ID | ord-6aa77afc762a42ec8d6e4b1ed64ec8ef |
|---|
| Source note | uspto-grants-2012_05 |
|---|
