Hydrazine → HCID 59443517, compound

Participants

Reaction Steps

Hydrazine (0.45 mL, 14.5 mmol) was added to a solution of methyl 3-[1-[(dimethyl-amino)sulfonyl]-4-(2,2-dimethylbutyl)-1H-imidazol-2-yl]propanoate (1 g, 2.9 mmol) in dry methanol (2 mL). After stirring at rt for 3 hr, volatiles were removed in vacuo, and chromatography of the resulting residue over silica eluting with 0-40% ethyl acetate/hexane afforded the title compound.

Provenance & Evidence