HCID 68674706, compound → HCID 59443511, compound

Participants

Reaction Steps

A solution of 2-{2-[3-(3,4-difluorophenyl)-1-methyl-1H-1,2,4-triazol-5-yl]ethyl}-4-(2,2-dimethylbutyl)-N,N-dimethyl-1H-imidazole-1-sulfonamide (90 mg, 0.19 mmol) in THF (4 mL) and 2 M HCl (4 mL) was heated at 80° C. overnight. The volatiles were removed and the residue was washed with ethyl acetate, basified with 1 N aqueous sodium hydroxide and extracted with ethyl acetate. The combined phases were dried over sodium sulfate and concentrated to afford the title compound. LC-MS: m/e (374M+H).

Provenance & Evidence