Phosphorus oxychloride → HCID 57468690, compound

HRID 1927853Notes

Reaction equation

HRID 1927853 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[C:9]1[CH:14]=[C:13]([C:15]([F:18])([F:17])[F:16])[NH:12][C:11](=O)[N:10]=1.O=P(Cl)(Cl)[Cl:22]>>[Cl:22][C:11]1[N:10]=[C:9]([C:3]2[CH:4]=[CH:5][C:6]([Cl:8])=[CH:7][C:2]=2[Cl:1])[CH:14]=[C:13]([C:15]([F:18])([F:17])[F:16])[N:12]=1

Participants

3

Reactant 2

HCID 24813Phosphorus oxychlorideHCID 57468691HCID 57468691, compound

Product 1

HCID 57468690HCID 57468690, compound

Procedure

The title compound was prepared from 4-(2,4-dichloro-phenyl)-6-trifluoromethyl-1H-pyrimidin-2-one (10.2 g, 0.033 mol) and phosphoroxychloride (50 ml) according to the general procedure I. Obtained as a light yellow solid (10.6 g, 98%). MS (ISP) 327.0 [(M+H)+]; mp 69.5° C.

Sources & evidence

ORD record
ord-79fed0ee9f434e4a81f49f20572d9960
Source dataset
uspto-grants-2012_05
Patent number
US08183262B2

Reaction notes

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