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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1927874Erstellt: 26. Oktober 2026

2-Chloro-4-(4-chlorophenyl)-6-cyclopropylpyrimidine → 2-(4-Bromo-imidazol-1-yl)-4-(4-chloro-phenyl)-6-cyclopropyl-pyrimidine

https://huagongshe.com/reaction/1927874

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt2-Chloro-4-(4-chlorophenyl)-6-cyclopropylpyrimidineHCID 57468616—
EduktHCID 178418934HCID 178418934—
Produkt2-(4-Bromo-imidazol-1-yl)-4-(4-chloro-phenyl)-6-cyclopropyl-pyrimidineHCID 57468738—

Reaktionsschritte

The title compound was prepared from 2-chloro-4-(4-chloro-phenyl)-6-cyclopropyl-pyrimidine (example A.13) (0.80 g, 3.0 mmol) and commercially available 4-bromo-imidazole (0.66 g, 4.50 mmol) according to the general procedure IVa. Obtained as a white solid (0.71 g, 63%). MS (ISP) 375.1 [(M+H)+].

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08183262B2
Quelldatensatzuspto-grants-2012_05
ORD IDord-1bf3681f19a84534b1ff67eb5e6a944e
Quellennotizuspto-grants-2012_05