2-Chloro-4-(3,4-dichlorophenyl)-6-trifluoromethylpyrimidine → 2-(4-Bromo-imidazol-1-yl)-4-(3,4-dichlorophenyl)-6-trifluoromethyl-pyrimidine

Participants

Reaction Steps

The title compound was prepared from 2-chloro-4-(3,4-dichloro-phenyl)-6-trifluoromethyl-pyrimidine (example A.7) (0.50 g, 1.53 mmol) and commercially available 4-bromo-imidazole (0.34 g, 2.31 mmol) according to the general procedure IVb. Obtained as a white solid (0.38 g, 57%). MS (ISP) 439.0 [(M+H)+]; mp 225.5° C.

Provenance & Evidence