HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HCID 57468657, Verbindung → 2-(4-Bromo-imidazol-1-yl)-4-methyl-6-(3-methyl-4-trifluoromethyl-phenyl)-pyrimidine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | HCID 57468657 | HCID 57468657 | — |
| Edukt | HCID 178418934 | HCID 178418934 | — |
| Produkt | 2-(4-Bromo-imidazol-1-yl)-4-methyl-6-(3-methyl-4-trifluoromethyl-phenyl)-pyrimidine | HCID 57468768 | — |
Reaktionsschritte
The title compound was prepared from 2-chloro-4-(3-methyl-4-trifluoromethyl-phenyl)-6-methyl-pyrimidine (example A.40) (0.40 g, 1.4 mmol) and commercially available 4-bromo-imidazole (0.31 g, 2.1 mmol) according to the general procedure IVa. Obtained as a light brown solid (0.54 g, 97%). MS (ISP) 399.0 [(M+H)+]; mp 157.5° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08183262B2 |
| Quelldatensatz | uspto-grants-2012_05 |
| ORD ID | ord-1174c47406a243f08f863a81bae99290 |
| Quellennotiz | uspto-grants-2012_05 |