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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1927916Generated: November 2, 2026

HCID 57468659, compound → 2-(4-Bromo-imidazol-1-yl)-4-(3,4-dichlorophenyl)-6-methyl-pyrimidine

https://huagongshe.com/reaction/1927916

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 57468659HCID 57468659—
ReactantHCID 178418934HCID 178418934—
Product2-(4-Bromo-imidazol-1-yl)-4-(3,4-dichlorophenyl)-6-methyl-pyrimidineHCID 57468775—

Reaction Steps

The title compound was prepared from 2-chloro-4-(3,4-dichloro-phenyl)-6-methyl-pyrimidine (example A.41) (0.4 g, 1.46 mmol) and commercially available 4-bromo-imidazole (0.32 g, 2.18 mmol) according to the general procedure IVa. Obtained as a light brown solid (0.33 g, 59%). MS (ISP) 385.0 [(M+H)+]; mp 219.5° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08183262B2
Source datasetuspto-grants-2012_05
ORD IDord-598f1434c62a41dba62ab5705ad39e58
Source noteuspto-grants-2012_05