2,4-Dibromo-1,3-thiazole → 2-(4-Bromo-thiazol-2-yl)-6-methyl-4-(4-trifluoromethyl-phenyl)-pyridine

Participants

Reaction Steps

The title compound was prepared from 2-iodo-6-methyl-4-(4-trifluoromethyl-phenyl)-pyridine (example A.31) (4.0 g, 9.36 mmol) and commercially available 2,4-dibromo-thiazole (2.53 g, 10.41 mmol) according to the general procedure IVc protocol b. Obtained as a light yellow solid (1.22 g, 31%). MS (ISP) 399.1 [(M+H)+] and 401.1 [(M+2+H)+].

Provenance & Evidence