HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-6-trifluoromethyl-4-(4-trifluoromethylphenyl)-pyridine → 2-(4-Iodo-imidazol-1-yl)-6-trifluoromethyl-4-(4-trifluoromethyl-phenyl)-pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-6-trifluoromethyl-4-(4-trifluoromethylphenyl)-pyridine | HCID 57468635 | — |
| Reactant | HCID 178506559 | HCID 178506559 | — |
| Product | 2-(4-Iodo-imidazol-1-yl)-6-trifluoromethyl-4-(4-trifluoromethyl-phenyl)-pyridine | HCID 57468806 | — |
Reaction Steps
The title compound was prepared from 2-chloro-6-trifluoromethyl-4-(4-trifluoromethyl-phenyl)-pyridine (example A.26) (2.0 g, 6.14 mmol) and commercially available 4-iodo-imidazole (1.31 g, 6.75 mmol) according to the general procedure IVa. Obtained as a white solid (1.90 g, 82%). MS (ISP) 484.1 [(M+H)+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08183262B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-4ed03d6661bb46fcb772c7d09d42d690 |
| Source note | uspto-grants-2012_05 |