HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,4-Dichloropyrimidine → HCID 57468808, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,4-Dichloropyrimidine | HCID 77531 | — |
| Reactant | 2-Iodo-4-methyl-6-(4-trifluoromethyl-phenyl)pyridine | HCID 57468682 | — |
| Catalyst | HCID 178461731 | HCID 178461731 | — |
| Product | HCID 57468808 | HCID 57468808 | — |
Reaction Steps
The title compound was prepared from 2-iodo-4-methyl-6-(4-trifluoromethyl-phenyl)-pyridine (example A.58) (2.55 g, 7.0 mmol), i-PrMgCl/ZnCl2 and commercially available 2,4-dichloropyrimidine (1.08 g, 7.21 mmol) according to the general procedure IVc protocol b. Obtained as a light brown solid (0.896 g, 37%). MS (ISP) 350.3 [(M+H)+] and 352 [(M+2+H)+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08183262B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-ee01ee855c9649fbbf37e785ea3b660e |
| Source note | uspto-grants-2012_05 |