化工社化工社 化学情報印刷レポート · 研究参考用
(R)-3-phenyllactic acid → HCID 66933229、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | (R)-3-phenyllactic acid | HCID 643327 | — |
| 反応物 | Aminotetrahydrocyclopenta[b]indole | HCID 66933239 | — |
| 生成物 | HCID 66933229 | HCID 66933229 | — |
反応手順
In Step B, the racemic aminotetrahydrocyclopenta[b]indole of formula (3) is resolved using (R)-2-hydroxy-3-phenylpropionic acid to obtain the salt of the (S)-aminotetrahydrocyclopenta[b]indole of formula (8). The salt formation is preferably done in isopropanol, with heating for about 1 to 6 hours, followed by cooling to obtain the desired enantiomer.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08183388B2 |
| 出典データセット | uspto-grants-2012_05 |
| ORD ID | ord-ccd5a068eccb479e833b05dadd499c71 |
| 出典メモ | uspto-grants-2012_05 |